Regional maps of Latin America with COVID-19-related information show a multi-colored tapestry reflecting different impacts from the pandemic and conditions in different countries, not unlike the multiple colors on maps of the United States used to reflect COVID-19-related conditions in various states and regions. Similarities among North, Central and South America also exist in key drivers of COVID-19 in particular locations, such as public health response, enforcement and compliance with public health guidelines, laws, rules and regulations, as well as social, political, cultural and economic factors.