The government will send $1 billion worth of federal grants for manufacturing, clean energy, farming, biotech and more to 21 regional partnerships across the nation, President Joe Biden and Commerce Secretary Gina Raimondo announced.

The 21 were chosen from 529 initial applicants vying for grants that were part of last year's $1.9 trillion coronavirus relief package. The Biden administration has repeatedly laid out a vision for the economy that is more self-sufficient and driven by high-tech manufacturing and the development of renewable energy.

"We designed this program by thinking about people and places," Biden said at a White House event. "This is about jobs in their communities for them, not having to leave or not having to go on unemployment. "

Unlike much of the pandemic aid that was meant to address immediate needs, the grants are part of a longer-term effort to revitalize parts of the country that have needed an economic jolt. The money will include funds for existing industries and capital for new ventures. The grants are the largest ever for local economic development provided by the Commerce Department, Raimondo said.

She said the effort is personal for her. Her father lost his job at a watch factory in Rhode Island

"The whole point of this is we're not going to let you get left behind as we transition to a more digital economy, to a more technical economy, to a green economy," Raimondo said in an interview.

The grants include $65.1 million for California to improve farm production and $25 million for a robotics cluster in Nebraska. Georgia gets $65 million for artificial intelligence. There is $63.7 million for lithium-based battery development in New York. Coal counties in West Virginia would receive $62.8 million to help with the shift to solar power and find new uses for abandoned mines.

"I can't tell you how much this means to our hardworking people in West Virginia," said that state's Democratic Sen. Joe Manchin, who attended the announcement virtually.

Raimondo estimated that the investments, which will be provided over five years as reimbursements, will result in at least 100,000 jobs.

Solidly Republican states such as Oklahoma and South Dakota received funding, and money also is going ahead of November's midterm elections toward political battlegrounds that could decide control of Congress. There is $44 million for regenerative medicine in New Hampshire, where Democrat Maggie Hassan is defending her U.S. Senate seat. Pennsylvania, which has an open Senate seat, is set to receive $62.7 million for robotics and artificial intelligence.

Raimondo said the winners were chosen based on merit rather than politics

"Let me ask you: How is this going to play out on the political scene?" Biden asked the Pennsylvania team attending Friday's event virtually.

Allegheny County Executive Rich Fitzgerald, a Democrat, quickly answered with a campaign ready line: "President Biden continues to invest in people and in jobs and in our future."

The massive amount of coronavirus aid at the start of Biden's tenure helped to accelerate job growth as the U.S. recovered from the pandemic. But accompanying the hiring was a burst of inflation that hit a 40-year peak this summer, crushing consumer sentiment and putting the administration on the defensive to show how its policies are helping the economy.

Even as much of the coronavirus money has been disbursed, the administration has said it still needs more to contain the disease and its variations. Biden sought $22.5 billion from Congress to address and prevent outbreaks, a figure that lawmakers reduced to $10 billion in negotiations. Additional funding was never passed by Congress despite confirmed cases that are now averaging about 90,000 daily.

White House press secretary Karine Jean-Pierre tried to minimize the lack of funding after the Food and Drug Administration on Wednesday approved modified booster shots of the vaccines. Jean-Pierre said booster shots would be available after the Labor Day holiday as the administration has worked with local partners.

The grants for economic development indicate that the relief package could have a multidecade impact that goes beyond the COVID-19 pandemic. The New Orleans area will receive $50 million to use hydrogen produced by wind power that does not cause carbon emissions, a meaningful change in Louisiana, a state that has long depended on fossil fuels.

"With clean hydrogen, we can remain an energy state — but become an energy state of the future that has less impact on the environment," said Michael Hecht, president and CEO of Greater New Orleans Inc., an economic development nonprofit. "When money and morality come together, you get stuff done."

Josh Boak reports for the Associated Press.

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