Walgreen Co., the nation’s largest pharmacy chain, will pay a record-setting $80 million in civil penalties for negligently allowing millions of oxycodone tablets and other prescription painkillers to be diverted to drug abusers and the black market.

The settlement, announced Tuesday in Miami by U.S. Attorney Wifredo Ferrer and Mark Trouville of the Drug Enforcement Administration, centered on the company’s distribution center in north Palm Beach County and six retail stores, which they said handed out nearly 10 million oxycodone tablets in 2011 alone.

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