In a big win for Actavis plc, the U.S. Court of Appeals for the Federal Circuit on Wednesday reaffirmed a lower court decision that Actavis’ patent for a popular low-estrogen birth control pill is valid and enforceable.

The drug, the brand-name contraceptive Lo Loestrin, has the lowest estrogen dose of any U.S.-approved oral contraceptive and has been extremely popular since its introduction a few years ago, with sales of $250 million last year. Wednesday’s ruling promises to extend Actavis’ market exclusivity on Lo Loestrin for 15 years, until the company’s patent expires in 2029.

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