Sanofi-Aventis has reached an agreement to buy Merck’s 50 percent stake in animal health joint venture Merial Limited for $4 billion in cash.

Established in 1997, Merial manufacturers vaccines for pets, livestock and wildlife, including the FRONTLINE brand of flea and tick control. It has approximately 5,400 employees in 150 countries and recorded $2.8 billion in sales last year.

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