When Neil Young wrote that "Southern change gonna come at last," he wasn't talking about cannabis—but he might as well have been in light of the recent and extraordinary developments in the cannabis industry in the southern United States. Florida is turning into the monster many expected; Louisiana is rounding into form, as is Arkansas; Alabama and Mississippi will launch programs this year; Georgia may even (finally) get off the ground; and Tennessee and the Carolinas look to be major players in the years to come. This article will examine on a state-by-state basis the fastest growing region in the cannabis industry.