On April 30, the U.S. Department of Justice (DOJ) issued a statement confirming its intent to reschedule cannabis from Schedule I to Schedule III under the 1970 Controlled Substances Act (CSA). Rescheduling cannabis from Schedule I to Schedule III represents a historic shift in federal policy with wide-ranging legal, regulatory, economic and health care implications. DOJ's action comes seven months after the formal recommendation by the U.S. Department of Health and Human Services (HHS) to the U.S. Drug Enforcement Agency (DEA) that cannabis be removed from Schedule I.