WASHINGTON — The U.S. Supreme Court on Monday set the stage for a landmark decision on the patentability of 21st century creations from software to biotech — an issue on which Supreme Court nominee Sonia Sotomayor could make a significant difference if confirmed.

Justices agreed to review the case Bilski v. Doll , a challenge to a ruling last fall by the Federal Circuit U.S. Court of Appeals that narrowed the patentability of so-called “business methods,” shorthand for a broad range of processes not tied to manufacturing.

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