SAN FRANCISCO — Lawyers from Cooley in San Diego and Palo Alto are advising pharmaceutical company Cypress Bioscience Inc., in its acquisition by Ramius LLC and Royalty Pharma.

The deal, valued at about $225 million in cash, ends a takeover battle that began in July. Under the terms, hedge fund Ramius will buy all of the Cypress shares it doesn’t already own for $6.50 a share. On Tuesday, Cypress had rejected a $6-per-share cash offer by Ramius, which had originally offered to buy Cypress for $4 a share in July.

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