SAN FRANCISCO — In a defeat for the product liability defense bar, the California Supreme Court on Monday ruled that both local and out-of-state residents can sue drug maker Bristol-Myers Squibb Co. in California state courts over claims that the blood thinning medication Plavix seriously harmed or killed patients.

The 4-3 decision cracks the door open to nationwide product liability cases in California, three years after the U.S. Supreme Court placed new restrictions on when courts may assert jurisdiction over a company that is headquartered outside the borders of its state.

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